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Drug ReportsCaprylic acid
Octanoic acid
Octanoic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target hydroxycarboxylic acid receptor 3 and cytochrome P450 4Z1.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
90 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Primary immunodeficiency diseasesD00008120713217
Diabetes mellitusD003920EFO_0000400E08-E1311125
Immunologic deficiency syndromesD007153D84.911215
AgingD000375GO_0007568R41.81112
Chronic inflammatory demyelinating polyradiculoneuropathyD020277EFO_1000868G61.81112
Streptococcal infectionsD013290EFO_100147611
Staphylococcal infectionsD013203A49.0111
Type 2 diabetes mellitusD003924EFO_0001360E1111
Immune system diseasesD007154D89.911
Peripheral nervous system diseasesD010523G6411
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Indications Phases 3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938C95314
SyndromeD0135771314
GastroparesisD018589EFO_1000948K31.84224
AdenocarcinomaD000230314
RecurrenceD012008414
Myelodysplastic syndromesD009190D46133
Myeloid leukemia acuteD015470C92.0223
PreleukemiaD011289133
Pancreatic neoplasmsD010190EFO_0003860C25213
Essential tremorD020329EFO_0003108G25.0323
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients437
Pancreatic ductal carcinomaD02144122
Acinar cell carcinomaD01826722
MycosesD009181B35-B4922
Non-hodgkin lymphomaD008228C85.922
LymphomaD008223C85.922
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.022
Sezary syndromeD012751C84.122
Biphenotypic leukemia acuteD015456C95.022
Mycosis fungoidesD009182C84.022
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
KetosisD007662R82.422
Type 1 diabetes mellitusD003922EFO_0001359E1022
Skin agingD015595EFO_000542222
Satiety responseD01252811
PsoriasisD011565EFO_0000676L4011
Gastric emptyingD00574611
Skin diseasesD012871L00-L9911
HypoglycemiaD007003E16.211
MicrobiotaD06430711
Diabetic footD017719EFO_100145911
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOctanoic acid
INNoctanoic acid
Description
Octanoic acid is a straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid. It has a role as an antibacterial agent, a human metabolite and an Escherichia coli metabolite. It is a straight-chain saturated fatty acid and a medium-chain fatty acid. It is a conjugate acid of an octanoate.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCC(=O)O
Identifiers
PDB
CAS-ID124-07-2
RxCUI
ChEMBL IDCHEMBL324846
ChEBI ID28837
PubChem CID379
DrugBankDB04519
UNII IDOBL58JN025 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HCAR3
HCAR3
CYP4Z1
CYP4Z1
Organism
Homo sapiens
Gene name
HCAR3
Gene synonyms
GPR109B, HCA3, HM74B, NIACR2
NCBI Gene ID
Protein name
hydroxycarboxylic acid receptor 3
Protein synonyms
G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, GTP-binding protein, hydroxy-carboxylic acid receptor 3, Niacin receptor 2, Nicotinic acid receptor 2, putative chemokine receptor
Uniprot ID
Mouse ortholog
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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22 adverse events reported
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